Applied Medical Informatics

The informatics group develops methods to quantitatively analyze clinical and preclinical image data in the scope of interdisciplinary research. One aim is to automate certain image segmentation or analysis steps, or at least minimize the required user input, to achieve a high level of user independence and therefore reproducibility.
Dr. rer. medic. F. Gremse

Selected publications

  1. Gremse F, Stärk M, Ehling J, Lammers T, Menzel JR, Kiessling F. Imalytics Preclinical: Interactive Analysis of Biomedical Volume Data. Theranostics. 2016;6(3)
  2. Gremse F, Doleschel D, Zafarnia Z, Babler A, Jahnen-Dechent W, Lammers T, Lederle W, Kiessling F. Hybrid µCT-FMT imaging and image analysis. JOVE. 2015;100
  3. Gremse F, Höfter A, Schwen LO, Kiessling F, Naumann U. GPU-Accelerated Sparse Matrix-Matrix Multiplication by Iterative Row Merging. SIAM J Sci Comput. 2015;37(1):C54–71.

  1. Rosenhain S, Al Rawashdeh W, Kiessling F, and Gremse F. Sensitivity and accuracy of hybrid fluorescence-mediated tomography in deep tissue regions. J Biophotonics. 2016 Nov 21. doi: 10.1002/jbio.201600232 [Epub ahead of print]
  2. Gremse F, Höfter A, Razik L, Kiessling F, and Naumann U. GPU-Accelerated Adjoint Algorithmic Differentiation. Comput Phys Commun. 2016;200:300‑311.
  3. Gremse F, Theek B, Kunjachan S, Lederle W, Pardo A, Barth S, Lammers T, Naumann U, and Kiessling F. Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid fluorescence-mediated tomography. Theranostics. 2014;4(10):960‑71.

Group members

Kerstin Küpper

Kerstin (M.Sc. Math) is working on numerical modelling in the context of diffuse optical tomography.

Stefanie Rosenhain

Stefanie (M.Sc. Biochemistry 2015 FSU Jena) is working on establishing molecular markers (fluorescent-labelled probes) for the detection of inflammatory bowel diseases via FMT-CT analysis in vivo.


S. Rosenhain

Grace Gyamfuah Yamoah

Grace (M.Tech. Software Engineering) develops software tools for data curation in the context of multimodal clinical and preclinical imaging studies.

Simin Zuo

Simin (M.Sc. Biomedical Engineering 2015 Tsinghua University, China) is working on quantitative parameter analysis using hybrid fluorescence-mediated tomography, in the context of angiogenesis, inflammation and drug delivery.


S. Zuo