- We permanently offer talented PhD students and postdocs the opportunity to join PMI in the field of PET-MRI, MPI and MRI. Please contact V. Schulz directly using the subject “application-pmi”.
Three PhD positions are available at the moment, to work on: I) the development and preclinical evaluation of liposomal nanomedicines; II) the development of a 3D-printed tumor angiogenesis model; and III) functional and molecular imaging of inflammation-associated angiogenesis. Please contact: T. Lammers for more details.
- PET: Development of a Dedicated Small Animal PET
- PET: Characterization of the TOFPET2 ASIC for high-performance Time-of-Flight PET/MRI applications
- PET: Development of a Advanced Monolithic PET Detector Block
- PET: Data Processing for a Fully Digital PET Insert
- PET: Energy Calibration of a PET with Multiple Gamma Lines
- MPI: Acquisition of fluid flow dynamics with MPI
- MRI: MR-compatibility of a preclinical, fully digital PET/MRI insert
- MRI: Referenceless MR thermometry to monitor tissue heating
- MRI: MR Fingerprinting with Water-Fat Separation
- MRI: Gridding Procedures for Spiral MRI
- Electrical Engineering: Development of an MRI-compatible switched capacitor power supply
M.Sc Thesis Project: The Nanomedicines and Theranostics group is offering an M.Sc thesis project position on Temperature-Responsive and Multi-Drug-Loaded Liposomes for Tumor Targeted Combination Therapy. The project aims at developing stimuli-responsive liposomes loaded with optimized combinations of hydrophilic and hydrophobic drugs, and evaluating their therapeutic potential in several in vitro and in vivo setups, including clinically relevant mouse models of pancreatic and colon cancer (for ultrasound-mediated heating and magnetic fluid hyperthermia (MFH), respectively). The overall objective of this work is to contribute to the development of better systems and strategies for drug targeting to tumors, and to come up with new (combination) concepts to really improve the treatment of cancer patients. Further information regarding the offer can be found here.
If you have further questions, please contact Ali Dadfar (PhD student).
B.Sc/M.Sc Thesis Project: The Institute for Experimental Molecular Imaging (ExMI) situated at the University Hospital Aachen and the Helmholtz Institute for Biomedical Engineering at RWTH Aachen University, is seeking highly motivated students to conduct their master/bachelor thesis under the Department of Nanomedicines and Theranostics headed by Prof. Twan Lammers. ExMI focuses on the development of novel contrast agents, imaging techniques and therapeutic approaches to characterize and treat cancer, cardiovascular and inflammatory disorders. The first project is based on Ultrasound Imaging and Microbubbles . Ultrasound is one of the most frequently used imaging modalities in clinical routine. It is real-time, safe, transportable and offers excellent spatial resolution and tissue contrast. With the introduction of microbubbles as contrast agents, ultrasound enables a detailed and quantitative characterization of tissue microvascularisation, perfusion and ischemia delineation, to name some. Microbubbles can also carry drugs, release them upon ultrasound-mediated microbubble destruction, and simultaneously enhance vascular permeability to increase drug deposition in tissues. The aim of this project is to load various model drugs such as fluorescent and photoacoustic dyes, chemotherapeutic agents in polymeric microbubbles and to evaluate various parameters that affects drug loading and delivery. The second project focuses on Gadolinium-based Nanoparticles for Theranostics Applications. Further information regarding the offer can be found here.
For more details, please contact Vertika Pathak (PhD student).